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KMID : 0380420160400010030
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Journal of Prventive Veterinary Medicine
2016 Volume.40 No. 1 p.30 ~ p.34
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Permeation characteristics of thermal paper ingredients using Franz diffusion cell
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Park Kyo-Hyun
Jung Se-Hoon
Shin Ho-Sang
Lee Seong-Eun
Lee Ki-Young
Kim Bae-Hwan
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Abstract
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The purpose of this study is to examine the exposure risk of thermal paper ingredients by analyzing skin permeation using an in vitro Franz cell. Thermal printer papers are usually used for receipt papers, and the skin of shop assistant is continuously exposed to hazardous ingredients of thermal papers. The skin permeation risk of thermal paper ingredients, including bisphenol A and toluene, was determined using an in vitro Franz diffusion cell method using hairless mouse full skin and human cadaver epidermis. Bisphenol A, a major component in each thermal paper, showed moderate skin penetration. Most skin absorption rates were similar in both hairless mouse full skin and human cadaver epidermis. The possible risk of exposure to toxic substances in thermal paper was confirmed from this study. These is results are expected to contribute to establishment of management regulations for thermal papers.
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KEYWORD
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Thermal paper, skin permeation, franz diffusion cell, exposure risk
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